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Neuregulin repellent signaling via ErbB4 restricts GABAergic interneurons to migratory paths from ganglionic eminence to cortical destinations

BACKGROUND: Cortical GABAergic interneurons (INs) are generated in the medial ganglionic eminence (MGE) and migrate tangentially into cortex. Because most, if not all, migrating MGE-derived INs express the neuregulin (NRG) receptor, ErbB4, we investigated influences of Nrg1 isoforms and Nrg3 on IN m...

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Detalles Bibliográficos
Autores principales: Li, Hao, Chou, Shen-Ju, Hamasaki, Tadashi, Perez-Garcia, Carlos G, O'Leary, Dennis DM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353847/
https://www.ncbi.nlm.nih.gov/pubmed/22376909
http://dx.doi.org/10.1186/1749-8104-7-10