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PCB 126 and Other Dioxin-Like PCBs Specifically Suppress Hepatic PEPCK Expression via the Aryl Hydrocarbon Receptor

Dioxins and dioxin-like compounds encompass a group of structurally related heterocyclic compounds that bind to and activate the aryl hydrocarbon receptor (AhR). The prototypical dioxin is 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), a highly toxic industrial byproduct that incites numerous adverse p...

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Detalles Bibliográficos
Autores principales: Zhang, Wenshuo, Sargis, Robert M., Volden, Paul A., Carmean, Christopher M., Sun, Xiao J., Brady, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353882/
https://www.ncbi.nlm.nih.gov/pubmed/22615911
http://dx.doi.org/10.1371/journal.pone.0037103