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Targeting of the Human Coagulation Factor IX Gene at rDNA Locus of Human Embryonic Stem Cells

BACKGROUND: Genetic modification is a prerequisite to realizing the full potential of human embryonic stem cells (hESCs) in human genetic research and regenerative medicine. Unfortunately, the random integration methods that have been the primary techniques used keep creating problems, and the prima...

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Detalles Bibliográficos
Autores principales:	Liu, Xionghao, Wu, Yong, Li, Zhuo, Yang, Junlin, Xue, Jinfeng, Hu, Youjin, Feng, Mai, Niu, Wenbin, Yang, Qiurui, Lei, Ming, Xia, Jiahui, Wu, Lingqian, Liang, Desheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353886/ https://www.ncbi.nlm.nih.gov/pubmed/22615895 http://dx.doi.org/10.1371/journal.pone.0037071

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