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Efficacy, Stability, and Biosafety of Sifuvirtide Gel as a Microbicide Candidate against HIV-1

Sifuvirtide is a proven effective HIV-1 entry inhibitor and its safety profile has been established for systemic administration. The present study evaluated the potential of sifuvirtide formulated in a universal gel for topical use as a microbicide candidate for preventing sexual transmission of HIV...

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Detalles Bibliográficos
Autores principales: Li, Liangzhu, Ben, Yinyin, Yuan, Songhua, Jiang, Shibo, Xu, Jianqing, Zhang, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353890/
https://www.ncbi.nlm.nih.gov/pubmed/22615996
http://dx.doi.org/10.1371/journal.pone.0037381