Cargando…
Crystal Structure of a Complex of DNA with One AT-Hook of HMGA1
We present here for the first time the crystal structure of an AT-hook domain. We show the structure of an AT-hook of the ubiquitous nuclear protein HMGA1, combined with the oligonucleotide d(CGAATTAATTCG)(2), which has two potential AATT interacting groups. Interaction with only one of them is foun...
Autores principales: | Fonfría-Subirós, Elsa, Acosta-Reyes, Francisco, Saperas, Núria, Pous, Joan, Subirana, Juan A., Campos, J. Lourdes |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353895/ https://www.ncbi.nlm.nih.gov/pubmed/22615915 http://dx.doi.org/10.1371/journal.pone.0037120 |
Ejemplares similares
-
Structure of the DNA Duplex d(ATTAAT)(2) with Hoogsteen Hydrogen Bonds
por: Acosta-Reyes, Francisco J., et al.
Publicado: (2015) -
The Dimerization State of the Mammalian High Mobility Group Protein AT-Hook 2 (HMGA2)
por: Frost, Lorraine, et al.
Publicado: (2015) -
The second AT-hook of the architectural transcription factor HMGA2 is determinant for nuclear localization and function
por: Cattaruzzi, Giacomo, et al.
Publicado: (2007) -
High Mobility Group AT-Hook 2 (HMGA2) Oncogenicity in Mesenchymal and Epithelial Neoplasia
por: Unachukwu, Uchenna, et al.
Publicado: (2020) -
Expression and Clinical Significance of High‐Mobility Group AT‐hook 2 (HMGA2) in Osteosarcoma
por: Cui, Juncheng, et al.
Publicado: (2022)