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Down-Regulation of AP-4 Inhibits Proliferation, Induces Cell Cycle Arrest and Promotes Apoptosis in Human Gastric Cancer Cells

BACKGROUND: AP-4 belongs to the basic helix-loop-helix leucine-zipper subgroup; it controls target gene expression, regulates growth, development and cell apoptosis and has been implicated in tumorigenesis. Our previous studies indicated that AP-4 was frequently overexpressed in gastric cancers and...

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Detalles Bibliográficos
Autores principales: Liu, Xinghua, Zhang, Bo, Guo, Yan, Liang, Qi, Wu, Changyao, Wu, Lei, Tao, Kaixiong, Wang, Guobin, Chen, Jianying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353913/
https://www.ncbi.nlm.nih.gov/pubmed/22615908
http://dx.doi.org/10.1371/journal.pone.0037096