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Coupling of Glucose Deprivation with Impaired Histone H2B Monoubiquitination in Tumors

Metabolic reprogramming is associated with tumorigenesis. However, glucose metabolism in tumors is poorly understood. Here, we report that glucose levels are significantly lower in bulk tumor specimens than those in normal tissues of the same tissue origins. We show that mono-ubiquitinated histone H...

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Detalles Bibliográficos
Autores principales: Urasaki, Yasuyo, Heath, Linda, Xu, C. Wilson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353945/
https://www.ncbi.nlm.nih.gov/pubmed/22615809
http://dx.doi.org/10.1371/journal.pone.0036775