K65R in Subtype C HIV-1 Isolates from Patients Failing on a First-Line Regimen Including d4T or AZT: Comparison of Sanger and UDP Sequencing Data

BACKGROUND: We and others have shown that subtype C HIV-1 isolates from patients failing on a regimen containing stavudine (d4T) or zidovudine (AZT) exhibit thymidine-associated mutations (TAMs) and K65R which can impair the efficacy of Tenofovir (TDF) at second line. Depending on the various studie...

Descripción completa

Detalles Bibliográficos
Autores principales: Recordon-Pinson, Patricia, Papuchon, Jennifer, Reigadas, Sandrine, Deshpande, Alaka, Fleury, Hervé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353948/
https://www.ncbi.nlm.nih.gov/pubmed/22615779
http://dx.doi.org/10.1371/journal.pone.0036549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353948/
https://www.ncbi.nlm.nih.gov/pubmed/22615779
http://dx.doi.org/10.1371/journal.pone.0036549

Ejemplares similares