Transcriptional Protein Sp1 Regulates LEDGF Transcription by Directly Interacting with Its Cis-Elements in GC-Rich Region of TATA-Less Gene Promoter

LEDGF/p75 interacts with DNA/protein to regulate gene expression and function. Despite the recognized diversity of function of LEDGF/p75, knowledge of its transregulation is in its infancy. Here we report that LEDGF/p75 gene is TATA-less, contains GC-rich cis elements and is transcriptionally regula...

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Detalles Bibliográficos
Autores principales: Singh, Dhirendra P., Bhargavan, Biju, Chhunchha, Bhavana, Kubo, Eri, Kumar, Anil, Fatma, Nigar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353957/
https://www.ncbi.nlm.nih.gov/pubmed/22615874
http://dx.doi.org/10.1371/journal.pone.0037012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353957/
https://www.ncbi.nlm.nih.gov/pubmed/22615874
http://dx.doi.org/10.1371/journal.pone.0037012

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