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Systems Biology Approach to Identify Gene Network Signatures for Colorectal Cancer

In this work, we integrated prior knowledge from gene signatures and protein interactions with gene set enrichment analysis (GSEA), and gene/protein network modeling together to identify gene network signatures from gene expression microarray data. We demonstrated how to apply this approach into dis...

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Detalles Bibliográficos
Autores principales: Sonachalam, Madhankumar, Shen, Jeffrey, Huang, Hui, Wu, Xiaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3354560/
https://www.ncbi.nlm.nih.gov/pubmed/22629282
http://dx.doi.org/10.3389/fgene.2012.00080