Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody

BACKGROUND: The form(s) of amyloid-β peptide (Aβ) associated with the pathology characteristic of Alzheimer's disease (AD) remains unclear. In particular, the neurotoxicity of intraneuronal Aβ accumulation is an issue of considerable controversy; even the existence of Aβ deposits within neurons...

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Detalles Bibliográficos
Autores principales: Youmans, Katherine L, Tai, Leon M, Kanekiyo, Takahisa, Stine, W Blaine, Michon, Sara-Claude, Nwabuisi-Heath, Evelyn, Manelli, Arlene M, Fu, Yifan, Riordan, Sean, Eimer, William A, Binder, Lester, Bu, Guojun, Yu, Chunjiang, Hartley, Dean M, LaDu, Mary Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355009/
https://www.ncbi.nlm.nih.gov/pubmed/22423893
http://dx.doi.org/10.1186/1750-1326-7-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355009/
https://www.ncbi.nlm.nih.gov/pubmed/22423893
http://dx.doi.org/10.1186/1750-1326-7-8

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