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Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody

BACKGROUND: The form(s) of amyloid-β peptide (Aβ) associated with the pathology characteristic of Alzheimer's disease (AD) remains unclear. In particular, the neurotoxicity of intraneuronal Aβ accumulation is an issue of considerable controversy; even the existence of Aβ deposits within neurons...

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Detalles Bibliográficos
Autores principales:	Youmans, Katherine L, Tai, Leon M, Kanekiyo, Takahisa, Stine, W Blaine, Michon, Sara-Claude, Nwabuisi-Heath, Evelyn, Manelli, Arlene M, Fu, Yifan, Riordan, Sean, Eimer, William A, Binder, Lester, Bu, Guojun, Yu, Chunjiang, Hartley, Dean M, LaDu, Mary Jo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355009/ https://www.ncbi.nlm.nih.gov/pubmed/22423893 http://dx.doi.org/10.1186/1750-1326-7-8

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