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Acetylcholine content and viability of cholinergic neurons are influenced by the activity of protein histidine phosphatase
BACKGROUND: The first mammalian protein histidine phosphatase (PHP) was discovered in the late 90s of the last century. One of the known substrates of PHP is ATP-citrate lyase (ACL), which is responsible - amongst other functions - for providing acetyl-CoA for acetylcholine synthesis in neuronal tis...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355010/ https://www.ncbi.nlm.nih.gov/pubmed/22436051 http://dx.doi.org/10.1186/1471-2202-13-31 |