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Acetylcholine content and viability of cholinergic neurons are influenced by the activity of protein histidine phosphatase

BACKGROUND: The first mammalian protein histidine phosphatase (PHP) was discovered in the late 90s of the last century. One of the known substrates of PHP is ATP-citrate lyase (ACL), which is responsible - amongst other functions - for providing acetyl-CoA for acetylcholine synthesis in neuronal tis...

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Detalles Bibliográficos
Autores principales: Eißing, Anna, Fischer, Daniel, Rauch, Ilka, Baumann, Anne, Schebb, Nils-Helge, Karst, Uwe, Rose, Karsten, Klumpp, Susanne, Krieglstein, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355010/
https://www.ncbi.nlm.nih.gov/pubmed/22436051
http://dx.doi.org/10.1186/1471-2202-13-31

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