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Protein kinase A enhances lipopolysaccharide-induced IL-6, IL-8, and PGE(2 )production by human gingival fibroblasts
OBJECTIVE: Periodontal disease is accompanied by inflammation of the gingiva and destruction of periodontal tissues, leading to alveolar bone loss in severe clinical cases. Interleukin (IL)-6, IL-8, and the chemical mediator prostaglandin E(2 )(PGE(2)) are known to play important roles in inflammato...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355011/ https://www.ncbi.nlm.nih.gov/pubmed/22452847 http://dx.doi.org/10.1186/1477-5751-11-10 |