The treatment of glioblastoma multiforme through activation of microglia and TRAIL induced by rAAV2-mediated IL-12 in a syngeneic rat model

BACKGROUND: Microglial cells are the predominant immune cells in malignant brain tumors, but tumors may release some factors to reduce their defensive functions. Restoration of the anti-cancer function of microglia has been proposed as a treatment modality for glioblastoma. We examined the effect of...

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Detalles Bibliográficos
Autores principales: Chiu, Tsung-Lang, Wang, Mei-Jan, Su, Chin-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355013/
https://www.ncbi.nlm.nih.gov/pubmed/22520731
http://dx.doi.org/10.1186/1423-0127-19-45

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355013/
https://www.ncbi.nlm.nih.gov/pubmed/22520731
http://dx.doi.org/10.1186/1423-0127-19-45

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