Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases

The ASXL1 gene is one of the most frequently mutated genes in malignant myeloid diseases. The ASXL1 protein belongs to protein complexes involved in the epigenetic regulation of gene expression. ASXL1 mutations are found in myeloproliferative neoplasms (MPN), myelodysplastic syndromes (MDS), chronic...

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Detalles Bibliográficos
Autores principales: Gelsi-Boyer, Véronique, Brecqueville, Mandy, Devillier, Raynier, Murati, Anne, Mozziconacci, Marie-Joelle, Birnbaum, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355025/
https://www.ncbi.nlm.nih.gov/pubmed/22436456
http://dx.doi.org/10.1186/1756-8722-5-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355025/
https://www.ncbi.nlm.nih.gov/pubmed/22436456
http://dx.doi.org/10.1186/1756-8722-5-12

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