Insufficient maintenance DNA methylation is associated with abnormal embryonic development

BACKGROUND: Early pregnancy loss (EPL) is a frustrating clinical problem, whose mechanisms are not completely understood. DNA methylation, which includes maintenance methylation and de novo methylation directed by DNA methyltransferases (DNMTs), is important for embryo development. Abnormal function...

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Detalles Bibliográficos
Autores principales: Yin, Li-Jun, Zhang, Yu, Lv, Ping-Ping, He, Wei-Hua, Wu, Yan-Ting, Liu, Ai-Xia, Ding, Guo-Lian, Dong, Min-Yue, Qu, Fan, Xu, Chen-Ming, Zhu, Xiao-Ming, Huang, He-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355050/
https://www.ncbi.nlm.nih.gov/pubmed/22413869
http://dx.doi.org/10.1186/1741-7015-10-26

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355050/
https://www.ncbi.nlm.nih.gov/pubmed/22413869
http://dx.doi.org/10.1186/1741-7015-10-26

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