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Insufficient maintenance DNA methylation is associated with abnormal embryonic development
BACKGROUND: Early pregnancy loss (EPL) is a frustrating clinical problem, whose mechanisms are not completely understood. DNA methylation, which includes maintenance methylation and de novo methylation directed by DNA methyltransferases (DNMTs), is important for embryo development. Abnormal function...
Autores principales: | Yin, Li-Jun, Zhang, Yu, Lv, Ping-Ping, He, Wei-Hua, Wu, Yan-Ting, Liu, Ai-Xia, Ding, Guo-Lian, Dong, Min-Yue, Qu, Fan, Xu, Chen-Ming, Zhu, Xiao-Ming, Huang, He-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355050/ https://www.ncbi.nlm.nih.gov/pubmed/22413869 http://dx.doi.org/10.1186/1741-7015-10-26 |
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