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Dietary L-arginine supplementation reduces Methotrexate-induced intestinal mucosal injury in rat

BACKGROUND: Arginine (ARG) and nitric oxide maintain the mucosal integrity of the intestine in various intestinal disorders. In the present study, we evaluated the effects of oral ARG supplementation on intestinal structural changes, enterocyte proliferation and apoptosis following methotrexate (MTX...

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Detalles Bibliográficos
Autores principales: Koppelmann, Tal, Pollak, Yulia, Mogilner, Jorge, Bejar, Jacob, Coran, Arnold G, Sukhotnik, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355056/
https://www.ncbi.nlm.nih.gov/pubmed/22545735
http://dx.doi.org/10.1186/1471-230X-12-41