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Dietary L-arginine supplementation reduces Methotrexate-induced intestinal mucosal injury in rat
BACKGROUND: Arginine (ARG) and nitric oxide maintain the mucosal integrity of the intestine in various intestinal disorders. In the present study, we evaluated the effects of oral ARG supplementation on intestinal structural changes, enterocyte proliferation and apoptosis following methotrexate (MTX...
Autores principales: | Koppelmann, Tal, Pollak, Yulia, Mogilner, Jorge, Bejar, Jacob, Coran, Arnold G, Sukhotnik, Igor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355056/ https://www.ncbi.nlm.nih.gov/pubmed/22545735 http://dx.doi.org/10.1186/1471-230X-12-41 |
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