Psip1/Ledgf p52 Binds Methylated Histone H3K36 and Splicing Factors and Contributes to the Regulation of Alternative Splicing

Increasing evidence suggests that chromatin modifications have important roles in modulating constitutive or alternative splicing. Here we demonstrate that the PWWP domain of the chromatin-associated protein Psip1/Ledgf can specifically recognize tri-methylated H3K36 and that, like this histone modi...

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Detalles Bibliográficos
Autores principales: Pradeepa, Madapura M., Sutherland, Heidi G., Ule, Jernej, Grimes, Graeme R., Bickmore, Wendy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355077/
https://www.ncbi.nlm.nih.gov/pubmed/22615581
http://dx.doi.org/10.1371/journal.pgen.1002717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355077/
https://www.ncbi.nlm.nih.gov/pubmed/22615581
http://dx.doi.org/10.1371/journal.pgen.1002717

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