Deletion of PTH Rescues Skeletal Abnormalities and High Osteopontin Levels in Klotho (−/−) Mice

Maintenance of normal mineral ion homeostasis is crucial for many biological activities, including proper mineralization of the skeleton. Parathyroid hormone (PTH), Klotho, and FGF23 have been shown to act as key regulators of serum calcium and phosphate homeostasis through a complex feedback mechan...

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Detalles Bibliográficos
Autores principales: Yuan, Quan, Sato, Tadatoshi, Densmore, Michael, Saito, Hiroaki, Schüler, Christiane, Erben, Reinhold G., Lanske, Beate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355080/
https://www.ncbi.nlm.nih.gov/pubmed/22615584
http://dx.doi.org/10.1371/journal.pgen.1002726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355080/
https://www.ncbi.nlm.nih.gov/pubmed/22615584
http://dx.doi.org/10.1371/journal.pgen.1002726

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