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Target Gene Analysis by Microarrays and Chromatin Immunoprecipitation Identifies HEY Proteins as Highly Redundant bHLH Repressors

HEY bHLH transcription factors have been shown to regulate multiple key steps in cardiovascular development. They can be induced by activated NOTCH receptors, but other upstream stimuli mediated by TGFß and BMP receptors may elicit a similar response. While the basic and helix-loop-helix domains exh...

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Detalles Bibliográficos
Autores principales: Heisig, Julia, Weber, David, Englberger, Eva, Winkler, Anja, Kneitz, Susanne, Sung, Wing-Kin, Wolf, Elmar, Eilers, Martin, Wei, Chia-Lin, Gessler, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355086/
https://www.ncbi.nlm.nih.gov/pubmed/22615585
http://dx.doi.org/10.1371/journal.pgen.1002728