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Target Gene Analysis by Microarrays and Chromatin Immunoprecipitation Identifies HEY Proteins as Highly Redundant bHLH Repressors
HEY bHLH transcription factors have been shown to regulate multiple key steps in cardiovascular development. They can be induced by activated NOTCH receptors, but other upstream stimuli mediated by TGFß and BMP receptors may elicit a similar response. While the basic and helix-loop-helix domains exh...
Autores principales: | Heisig, Julia, Weber, David, Englberger, Eva, Winkler, Anja, Kneitz, Susanne, Sung, Wing-Kin, Wolf, Elmar, Eilers, Martin, Wei, Chia-Lin, Gessler, Manfred |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355086/ https://www.ncbi.nlm.nih.gov/pubmed/22615585 http://dx.doi.org/10.1371/journal.pgen.1002728 |
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