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Global Analysis of the Evolution and Mechanism of Echinocandin Resistance in Candida glabrata

The evolution of drug resistance has a profound impact on human health. Candida glabrata is a leading human fungal pathogen that can rapidly evolve resistance to echinocandins, which target cell wall biosynthesis and are front-line therapeutics for Candida infections. Here, we provide the first glob...

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Detalles Bibliográficos
Autores principales: Singh-Babak, Sheena D., Babak, Tomas, Diezmann, Stephanie, Hill, Jessica A., Xie, Jinglin Lucy, Chen, Ying-Lien, Poutanen, Susan M., Rennie, Robert P., Heitman, Joseph, Cowen, Leah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355103/
https://www.ncbi.nlm.nih.gov/pubmed/22615574
http://dx.doi.org/10.1371/journal.ppat.1002718