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A Meta-Analysis of Caspase 9 Polymorphisms in Promoter and Exon Sequence on Cancer Susceptibility

BACKGROUND: Caspases are important regulators and executioners in apoptosis pathway and have been defined as either tumor suppressors or oncogenes. Polymorphisms in promoter and exon of caspase 9 were shown to confer genetic susceptibility to multiple cancers, but the results were inconsistent. To a...

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Detalles Bibliográficos
Autores principales: Xu, Wei, Jiang, Shengqiang, Xu, Yuanyuan, Chen, Bo, Li, Yan, Zong, Feng, Zhao, Weihong, Wu, Jianqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355128/
https://www.ncbi.nlm.nih.gov/pubmed/22616010
http://dx.doi.org/10.1371/journal.pone.0037443