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Feedback within the Inter-Cellular Communication and Tumorigenesis in Carcinomas
The classical somatic mutation theory (SMT) of carcinogenesis and metastasis postulates that malignant transformation occurs in cells that accumulate a sufficient amount of mutations in the appropriate oncogenes and/or tumor suppressor genes. These mutations result in cell-autonomous activation of t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355145/ https://www.ncbi.nlm.nih.gov/pubmed/22615799 http://dx.doi.org/10.1371/journal.pone.0036719 |