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Sphingosine Kinase 1 Deficiency Exacerbates LPS-Induced Neuroinflammation
The pathogenesis of inflammation in the central nervous system (CNS), which contributes to numerous neurodegenerative diseases and results in encephalopathy and neuroinflammation, is poorly understood. Sphingolipid metabolism plays a crucial role in maintaining cellular processes in the CNS, and thu...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355156/ https://www.ncbi.nlm.nih.gov/pubmed/22615770 http://dx.doi.org/10.1371/journal.pone.0036475 |