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Association Analysis of the Extended MHC Region in Celiac Disease Implicates Multiple Independent Susceptibility Loci

Celiac disease is a common autoimmune disease caused by sensitivity to the dietary protein gluten. Forty loci have been implicated in the disease. All disease loci have been characterized as low-penetrance, with the exception of the high-risk genotypes in the HLA-DQA1 and HLA-DQB1 genes, which are n...

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Detalles Bibliográficos
Autores principales: Ahn, Richard, Ding, Yuan Chun, Murray, Joseph, Fasano, Alessio, Green, Peter H. R., Neuhausen, Susan L., Garner, Chad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355177/
https://www.ncbi.nlm.nih.gov/pubmed/22615847
http://dx.doi.org/10.1371/journal.pone.0036926