A proprotein convertase/MMP-14 proteolytic cascade releases a novel 40 kDa vasculostatin from tumor suppressor BAI1

Brain angiogenesis inhibitor 1 (BAI1), an orphan GPCR-type seven transmembrane receptor, was recently found mutated or silenced in multiple human cancers and can interfere with tumor growth when overexpressed. Yet, little is known about the molecular mechanisms through which this novel tumor suppres...

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Detalles Bibliográficos
Autores principales: Cork, Sarah M., Kaur, Balveen, Devi, Narra S., Cooper, Lee, Saltz, Joel H., Sandberg, Eric M., Kaluz, Stefan, Van Meir, Erwin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355202/
https://www.ncbi.nlm.nih.gov/pubmed/22330140
http://dx.doi.org/10.1038/onc.2012.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355202/
https://www.ncbi.nlm.nih.gov/pubmed/22330140
http://dx.doi.org/10.1038/onc.2012.1

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