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Back to the Future: Lessons Learned in Modern Target-based and Whole-Cell Lead Optimization of Antimalarials
Antimalarial drug discovery has historically benefited from the whole-cell (phenotypic) screening approach to identify lead molecules in the search for new drugs. However over the past two decades there has been a shift in the pharmaceutical industry to move away from whole-cell screening to target-...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Bentham Science Publishers
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355380/ https://www.ncbi.nlm.nih.gov/pubmed/22242845 http://dx.doi.org/10.2174/156802612799362977 |