Transport and Metabolism at Blood–Brain Interfaces and in Neural Cells: Relevance to Bilirubin-Induced Encephalopathy

Bilirubin, the end-product of heme catabolism, circulates in non-pathological plasma mostly as a protein-bound species. When bilirubin concentration builds up, the free fraction of the molecule increases. Unbound bilirubin then diffuses across blood–brain interfaces (BBIs) into the brain, where it a...

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Detalles Bibliográficos
Autores principales: Gazzin, Silvia, Strazielle, Nathalie, Tiribelli, Claudio, Ghersi-Egea, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355510/
https://www.ncbi.nlm.nih.gov/pubmed/22629246
http://dx.doi.org/10.3389/fphar.2012.00089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355510/
https://www.ncbi.nlm.nih.gov/pubmed/22629246
http://dx.doi.org/10.3389/fphar.2012.00089

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