Transport and Metabolism at Blood–Brain Interfaces and in Neural Cells: Relevance to Bilirubin-Induced Encephalopathy

Bilirubin, the end-product of heme catabolism, circulates in non-pathological plasma mostly as a protein-bound species. When bilirubin concentration builds up, the free fraction of the molecule increases. Unbound bilirubin then diffuses across blood–brain interfaces (BBIs) into the brain, where it a...

Descripción completa

Detalles Bibliográficos
Autores principales: Gazzin, Silvia, Strazielle, Nathalie, Tiribelli, Claudio, Ghersi-Egea, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355510/
https://www.ncbi.nlm.nih.gov/pubmed/22629246
http://dx.doi.org/10.3389/fphar.2012.00089

Ejemplares similares

Ejemplares similares