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Plant Lessons: Exploring ABCB Functionality Through Structural Modeling

In contrast to mammalian ABCB1 proteins, narrow substrate specificity has been extensively documented for plant orthologs shown to catalyze the transport of the plant hormone, auxin. Using the crystal structures of the multidrug exporters Sav1866 and MmABCB1 as templates, we have developed structura...

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Detalles Bibliográficos
Autores principales: Bailly, Aurélien, Yang, Haibing, Martinoia, Enrico, Geisler, Markus, Murphy, Angus S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355715/
https://www.ncbi.nlm.nih.gov/pubmed/22639627
http://dx.doi.org/10.3389/fpls.2011.00108