Conformational Dynamics of Insulin

We have exploited a prandial insulin analog to elucidate the underlying structure and dynamics of insulin as a monomer in solution. A model was provided by insulin lispro (the active component of Humalog(®); Eli Lilly and Co.). Whereas NMR-based modeling recapitulated structural relationships of ins...

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Detalles Bibliográficos
Autores principales: Hua, Qing-Xin, Jia, Wenhua, Weiss, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355934/
https://www.ncbi.nlm.nih.gov/pubmed/22649374
http://dx.doi.org/10.3389/fendo.2011.00048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355934/
https://www.ncbi.nlm.nih.gov/pubmed/22649374
http://dx.doi.org/10.3389/fendo.2011.00048

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