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Low Affinity GPCRs for Metabolic Intermediates: Challenges for Pharmacologists
The discovery that a number of metabolites and metabolic intermediates can act through G protein-coupled receptors has attracted great interest in the field and has led to new therapeutic targets for diseases such as hypertension, type 2 diabetes, inflammation, and metabolic syndrome. However, the l...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Research Foundation
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355937/ https://www.ncbi.nlm.nih.gov/pubmed/22649402 http://dx.doi.org/10.3389/fendo.2012.00001 |