Drug Discovery Opportunities and Challenges at G Protein Coupled Receptors for Long Chain Free Fatty Acids

Discovery of G protein coupled receptors for long chain free fatty acids (FFAs), FFA1 (GPR40) and GPR120, has expanded our understanding of these nutrients as signaling molecules. These receptors have emerged as important sensors for FFA levels in the circulation or the gut lumen, based on evidence...

Descripción completa

Detalles Bibliográficos
Autores principales: Holliday, Nicholas D., Watson, Sarah-Jane, Brown, Alastair J. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355945/
https://www.ncbi.nlm.nih.gov/pubmed/22649399
http://dx.doi.org/10.3389/fendo.2011.00112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355945/
https://www.ncbi.nlm.nih.gov/pubmed/22649399
http://dx.doi.org/10.3389/fendo.2011.00112

Ejemplares similares