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Biological Significance of GPCR Heteromerization in the Neuro-Endocrine System

Clustering of proteins in higher order complexes is a common theme in biology and profoundly influences protein function. The idea that seven-transmembrane spanning G protein-coupled receptors (GPCRs) might form dimers or higher order oligomeric complexes has been formulated more than 20 years ago....

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Detalles Bibliográficos
Autores principales: Kamal, Maud, Jockers, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355952/
https://www.ncbi.nlm.nih.gov/pubmed/22649357
http://dx.doi.org/10.3389/fendo.2011.00002