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Regulation of Ubiquitination-Mediated Protein Degradation by Survival Kinases in Cancer
The ubiquitin–proteasome system is essential for multiple physiological processes via selective degradation of target proteins and has been shown to plays a critical role in human cancer. Activation of oncogenic factors and inhibition of tumor suppressors have been shown to be essential for cancer d...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Research Foundation
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355968/ https://www.ncbi.nlm.nih.gov/pubmed/22649777 http://dx.doi.org/10.3389/fonc.2012.00015 |