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Cul4A is an oncogene in malignant pleural mesothelioma

Cullin 4A (Cul4A) is important in cell survival, development, growth and the cell cycle, but its role in mesothelioma has not been studied. For the first time, we identified amplification of the Cul4A gene in four of five mesothelioma cell lines. Consistent with increased Cul4A gene copy number, we...

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Detalles Bibliográficos
Autores principales: Hung, Ming-Szu, Mao, Jian-Hua, Xu, Zhidong, Yang, Cheng-Ta, Yu, Jau-Song, Harvard, Chansonette, Lin, Yu-Ching, Bravo, Dawn Therese, Jablons, David M, You, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355981/
https://www.ncbi.nlm.nih.gov/pubmed/19929949
http://dx.doi.org/10.1111/j.1582-4934.2009.00971.x