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Extracellular Domain N-Glycosylation Controls Human Thrombopoietin Receptor Cell Surface Levels
The thrombopoietin receptor (TpoR) is a type I transmembrane protein that mediates the signaling functions of thrombopoietin (Tpo) in regulating megakaryocyte differentiation, platelet formation, and hematopoietic stem cell renewal. We probed the role of each of the four extracellular domain putativ...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355985/ https://www.ncbi.nlm.nih.gov/pubmed/22649382 http://dx.doi.org/10.3389/fendo.2011.00071 |