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Extracellular Domain N-Glycosylation Controls Human Thrombopoietin Receptor Cell Surface Levels

The thrombopoietin receptor (TpoR) is a type I transmembrane protein that mediates the signaling functions of thrombopoietin (Tpo) in regulating megakaryocyte differentiation, platelet formation, and hematopoietic stem cell renewal. We probed the role of each of the four extracellular domain putativ...

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Detalles Bibliográficos
Autores principales: Albu, Roxana I., Constantinescu, Stefan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355985/
https://www.ncbi.nlm.nih.gov/pubmed/22649382
http://dx.doi.org/10.3389/fendo.2011.00071