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Ribonucleotide Reductase Inhibitors: A New Look at an Old Target for Radiosensitization
Ribonucleotide reductase (RR), the rate limiting enzyme in the synthesis and repair of DNA, has been studied as a target for inhibition in the treatment of cancer for many years. While some researchers have focused on RR inhibitors as chemotherapeutic agents, particularly in hematologic malignancies...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Research Foundation
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356024/ https://www.ncbi.nlm.nih.gov/pubmed/22655252 http://dx.doi.org/10.3389/fonc.2011.00056 |