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Insulin-Like Growth Factor Binding Proteins: A Structural Perspective

Insulin-like growth factor binding proteins (IGFBP-1 to -6) bind insulin-like growth factors-I and -II (IGF-I and IGF-II) with high affinity. These binding proteins maintain IGFs in the circulation and direct them to target tissues, where they promote cell growth, proliferation, differentiation, and...

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Detalles Bibliográficos
Autores principales: Forbes, Briony E., McCarthy, Peter, Norton, Raymond S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356058/
https://www.ncbi.nlm.nih.gov/pubmed/22654863
http://dx.doi.org/10.3389/fendo.2012.00038