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Defying the Stereotype: Non-Canonical Roles of the Peptide Hormones Guanylin and Uroguanylin
The peptide hormones uroguanylin and guanylin have been traditionally thought to be mediators of fluid–ion homeostasis in the vertebrate intestine. They serve as ligands for receptor guanylyl cyclase C (GC-C), and both receptor and ligands are expressed predominantly in the intestine. Ligand binding...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356075/ https://www.ncbi.nlm.nih.gov/pubmed/22654795 http://dx.doi.org/10.3389/fendo.2011.00014 |