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Defying the Stereotype: Non-Canonical Roles of the Peptide Hormones Guanylin and Uroguanylin

The peptide hormones uroguanylin and guanylin have been traditionally thought to be mediators of fluid–ion homeostasis in the vertebrate intestine. They serve as ligands for receptor guanylyl cyclase C (GC-C), and both receptor and ligands are expressed predominantly in the intestine. Ligand binding...

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Detalles Bibliográficos
Autores principales: Basu, Nirmalya, Visweswariah, Sandhya Srikant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356075/
https://www.ncbi.nlm.nih.gov/pubmed/22654795
http://dx.doi.org/10.3389/fendo.2011.00014