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Neuroregenerative Mechanisms of Allopregnanolone in Alzheimer’s Disease
The proliferative pool and regenerative potential of neural stem cells diminishes with age, a phenomenon that may be exacerbated in prodromal and mild Alzheimer’s disease (AD) brains. In parallel, the neuroactive progesterone metabolite, allopregnanolone (APα), along with a host of other factors, is...
Autores principales: | Irwin, Ronald W., Wang, Jun Ming, Chen, Shuhua, Brinton, Roberta Diaz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356095/ https://www.ncbi.nlm.nih.gov/pubmed/22654847 http://dx.doi.org/10.3389/fendo.2011.00117 |
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