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Passive targeting of ischemic-reperfused myocardium with adenosine-loaded silica nanoparticles

Pharmacological agents suggested for infarct size limitation have serious side effects when used at cardioprotective doses which hinders their translation into clinical practice. The solution to the problem might be direct delivery of cardioprotective drugs into ischemic-reperfused myocardium. In th...

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Detalles Bibliográficos
Autores principales: Galagudza, Michael, Korolev, Dmitry, Postnov, Viktor, Naumisheva, Elena, Grigorova, Yulia, Uskov, Ivan, Shlyakhto, Eugene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356166/
https://www.ncbi.nlm.nih.gov/pubmed/22619519
http://dx.doi.org/10.2147/IJN.S29511