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PLGA nanoparticle-mediated delivery of tumor antigenic peptides elicits effective immune responses

The peptide vaccine clinical trials encountered limited success because of difficulties associated with stability and delivery, resulting in inefficient antigen presentation and low response rates in patients with cancer. The purpose of this study was to develop a novel delivery approach for tumor a...

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Detalles Bibliográficos
Autores principales: Ma, Wenxue, Chen, Mingshui, Kaushal, Sharmeela, McElroy, Michele, Zhang, Yu, Ozkan, Cengiz, Bouvet, Michael, Kruse, Carol, Grotjahn, Douglas, Ichim, Thomas, Minev, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356185/
https://www.ncbi.nlm.nih.gov/pubmed/22619507
http://dx.doi.org/10.2147/IJN.S29506