Oridonin nanosuspension was more effective than free oridonin on G(2)/M cell cycle arrest and apoptosis in the human pancreatic cancer PANC-1 cell line

Oridonin, a diterpenoid isolated from Rabdosia rubescencs, has been reported to have antitumor effects. However, low solubility has limited its clinical applications. Preparation of drugs in the form of nanosuspensions is an extensively utilized protocol. In this study, we investigated the anticance...

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Detalles Bibliográficos
Autores principales: Qi, Xiaoli, Zhang, Dianrui, Xu, Xia, Feng, Feifei, Ren, Guijie, Chu, Qianqian, Zhang, Qiang, Tian, Keli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356194/
https://www.ncbi.nlm.nih.gov/pubmed/22619528
http://dx.doi.org/10.2147/IJN.S29483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356194/
https://www.ncbi.nlm.nih.gov/pubmed/22619528
http://dx.doi.org/10.2147/IJN.S29483

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