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Evidence that an APOE ε4 'double whammy' increases risk for Alzheimer's disease

Temporal lobe epilepsy (TLE) is associated with some of the same neuropathological features as those reported for early stages of typical Alzheimer's disease (AD). The APOE ε4 allele is associated with a gene-dose-dependent increase in AD risk and in the severity of amyloid-β (Aβ) pathology. In...

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Detalles Bibliográficos
Autores principales: Caesar, Ina, Gandy, Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356233/
https://www.ncbi.nlm.nih.gov/pubmed/22502767
http://dx.doi.org/10.1186/1741-7015-10-36

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